How Aging Affects T Lymphocyte-Mediated Immunity
نویسندگان
چکیده
منابع مشابه
How Aging Affects T Lymphocyte-Mediated Immunity
age-dependent decline in immune responses while autoimmune diseases increase in incidence. The authors hypothesize that the same defects that account for the decreased ability to generate protective immune responses also contribute to the increased risk of autoimmunity. The major risk factor for autoimmunity in old age appears to be the reshaping of the peripheral T cell receptor repertoire, wh...
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The aim of this study was to evaluate the immune system and lymphocyte function in 41 Iranian β-thalassemic patients and 50 controls, ages ranging from 2 to 18 years. The patients consisted of 20 splenectomized and 21 non-splenectomized patients. They were treated with Desferal, and had received repeated blood transfusion. Laboratory investigations included measurement of total T lymphocyt...
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Background and Aims: Rubella is predominantly a childhood disease that is endemic throughout the world and when rubella outbreaks occur, they are accompanied by birth defects following congenital rubella syndrome. Immunity to rubella virus as a teratogenic agent has an important role for prevention of these serious congenital defects. Lymphocyte proliferation assay is a way for investigation of...
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Five types of hypersensitivity reactions have been described: types I, II, III and V depend on the interaction of antigen with antibody and have been termed immediate; type IV depends on the interaction of antigen with T lymphocytes and has been called delayed-type hypersensitivity, or DTH. The DTH reaction involves cellular activation of T-helper cells (CD4+) and/or cytotoxic T cells (CD8+ CTL...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2013
ISSN: 1664-3224
DOI: 10.3389/fimmu.2013.00296